49ers
| 12/31/69 | 7:00 PM EST | |
| | ||
Injuries
| Date | Player | Status |
|---|---|---|
| 2025-09-16 | Ben Bartch | Doubtful |
| 2025-09-16 | Spencer Burford | Questionable |
| 2025-09-15 | Ben Bartch | Doubtful |
| 2025-09-15 | Spencer Burford | Questionable |
| 2025-09-15 | Brock Purdy | Out |
| 2025-09-14 | Ben Bartch | Questionable |
| 2025-09-14 | Jordan James | Out |
| 2025-09-14 | Jauan Jennings | Questionable |
| 2025-09-14 | Nick Martin | Out |
| 2025-09-14 | Siran Neal | Questionable |
| 2025-09-14 | Austen Pleasants | Out |
| 2025-09-12 | Yetur Gross-Matos | Questionable |
| 2025-09-12 | Brock Purdy | Out |
| 2025-09-12 | Jordan Watkins | Questionable |
| 2025-09-11 | Brock Purdy | Doubtful |
| 2025-09-11 | Jordan Watkins | Questionable |
Transactions
| Date | Transaction |
|---|---|
| 2025-09-11 | Signed TE Messiah Swinson to the practice squad. |
| 2025-09-10 | Signed K Eddy Pineiro to the active roster. |
